SCHEMBL21295980

SCHEMBL21295980

[c]1cc2cccc(-c3ccncc3)c2o1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
MAPT P10636 3/20 0.39
ALDH1A1 P00352 3/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TNF P01375 2/20 0.38
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
PIK3CD O00329 1/20 0.37
MAPK11 Q15759 1/20 0.34
MAPK14 Q16539 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21296179 0.84 ADORA3 (0.40) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL21295698 0.82 CYP11B1 (0.47) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL21295627 0.73 KDM4E (0.44) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL21295801 0.72 PIK3CD (0.44) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL28217059 0.71 SMN1; SMN2 (0.46) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL4622015 0.70 ADORA3 (0.37) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL26259714 0.69 ALDH1A1 (0.53) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL767227 0.66 ALDH1A1 (0.40) ALDH1A1LMNAHPGDHSD17B10TSHR
SCHEMBL30756642 0.66 TNF (0.63) NPC1RAB9ASMN1; SMN2MAPTALDH1A1
SCHEMBL13203236 0.66 TNF (0.63) NPC1RAB9ASMN1; SMN2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
CN-112912372-A Cyclic azine compound, material for organic electroluminescent element, electron transport material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2021-06-04 CN disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
WO-2019163959-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCNET ELEMENT, AND ELECTRON-TRANSPORTING MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2019-08-29 WO disclosed