Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3378262 | 0.83 | MAOB (0.39) | ADORA3MAOAMAOBADORA1ADORA2A | |
| SCHEMBL21296179 | 0.78 | ADORA3 (0.40) | ADORA3MAOBADORA1ADORA2AALDH1A1 | |
| SCHEMBL21295627 | 0.71 | KDM4E (0.44) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL21295980 | 0.70 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30354037 | 0.68 | ACHE (0.64) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL197690 | 0.68 | ACHE (0.64) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30169568 | 0.68 | ACHE (0.64) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL598761 | 0.68 | TSHR (0.53) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12990204 | 0.68 | ALDH1A1 (0.67) | ALDH1A1CYP2A6NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5310084 | 0.67 | NPC1 (0.39) | ALDH1A1NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871358-A1 | BENZOFURANYL ALKANAMINE DERIVATIVES AND USES THEREOF AS 5-HT2C AGONISTS | Wyeth (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006116151-A1 | BENZOFURANYL ALKANAMINE DERIVATIVES AND USES THEREOF AS 5-HT2C AGONISTS | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |