SCHEMBL21296083

SCHEMBL21296083

CO[Si](CCc1ccccc1CSC#N)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
TAAR1 Q96RJ0 1/20 0.32
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
EGFR P00533 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALPL P05186 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139732 0.82 TAAR1 (0.42) MTNR1AMTNR1BTAAR1MAPTALDH1A1
SCHEMBL30276868 0.82 TAAR1 (0.42) MTNR1AMTNR1BTAAR1MAPTALDH1A1
SCHEMBL233078 0.80 ALDH1A1 (0.38) MTNR1AMTNR1BTAAR1MAPTNPC1
SCHEMBL8764187 0.76 CYP1A2 (0.42) MAPTNPC1RAB9ASMN1; SMN2NPSR1
SCHEMBL6332009 0.75 MTNR1A (0.41) MTNR1AMTNR1BTAAR1MAPTNPSR1
SCHEMBL7906930 0.74 TAAR1 (0.42) MTNR1AMTNR1BTAAR1ALDH1A1
SCHEMBL20738370 0.74 IDO1 (0.48) TAAR1MAPTSMN1; SMN2ALDH1A1
SCHEMBL2864494 0.74 MTNR1A (0.37) MTNR1AMTNR1BTAAR1ALDH1A1
SCHEMBL3859966 0.74 IDO1 (0.38) MTNR1AMTNR1BTAAR1MAPTALDH1A1
SCHEMBL1968082 0.72 TAAR1 (0.60) MTNR1AMTNR1BTAAR1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075101-A1 SURFACE TREATMENT Interphase Materials, Inc (US) 2025-03-06 US disclosed
US-12146071-B2 Surface treatment INTERPHASE MATERIALS INC. (US) 2024-11-19 US disclosed
EP-4106913-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X Genomics, Inc. (US) 2022-12-28 EP disclosed
US-20220016624-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X GENOMICS, INC. 2022-01-20 US disclosed
EP-3697860-A2 SURFACE TREATMENT Interphase Materials Inc. (US) 2020-08-26 EP disclosed
US-20200231842-A1 Surface Treatment INTERPHASE MAT INC (US) 2020-07-23 US disclosed
WO-2019164546-A2 SURFACE TREATMENT INTERPHASE MATERIALS INC. (US) 2019-08-29 WO disclosed