SCHEMBL233078

SCHEMBL233078

CO[Si](CCc1ccccc1CC#N)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
ATP4A P20648 1/20 0.33
ATP4B P51164 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
FFAR1 O14842 1/20 0.31
FFAR4 Q5NUL3 1/20 0.31
MEN1 O00255 2/20 0.31
MAPT P10636 2/20 0.31
KMT2A Q03164 2/20 0.31
PKM P14618 1/20 0.31
MAPK1 P28482 1/20 0.31
HTR2A P28223 1/20 0.31
NPC1 O15118 1/20 0.31
THRB P10828 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30276868 0.85 TAAR1 (0.42) ALDH1A1MTNR1AMTNR1BTAAR1MAPT
SCHEMBL139732 0.85 TAAR1 (0.42) ALDH1A1MTNR1AMTNR1BTAAR1MAPT
SCHEMBL233930 0.83 ALDH1A1 (0.36) ALDH1A1HPGDATP4AATP4BFFAR1
SCHEMBL21296083 0.80 MTNR1A (0.33) ALDH1A1MTNR1AMTNR1BTAAR1NPSR1
SCHEMBL6332009 0.78 MTNR1A (0.41) ALDH1A1HPGDMTNR1AMTNR1BTAAR1
SCHEMBL7906930 0.77 TAAR1 (0.42) ALDH1A1HPGDMTNR1AMTNR1BTAAR1
SCHEMBL3859966 0.77 IDO1 (0.38) ALDH1A1MTNR1AMTNR1BTAAR1MAPT
SCHEMBL2864494 0.77 MTNR1A (0.37) ALDH1A1MTNR1AMTNR1BTAAR1TSHR
SCHEMBL6208513 0.77 ALDH1A1 (0.41) ALDH1A1HPGDATP4AATP4BTAAR1
SCHEMBL1968082 0.74 TAAR1 (0.60) ALDH1A1MTNR1AMTNR1BTAAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0987286-B1 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING (US) 2004-07-14 EP claimed
EP-0987286-A2 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-03-22 EP claimed
US-6013705-A Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-01-11 US claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
US-8597508-B2 Sol-gel monolithic column with optical window and method of making UNIVERSITY OF SOUTH FLORIDA (US) 2013-12-03 US disclosed
US-20120000850-A1 SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING UNIVERSITY OF SOUTH FLORIDA (US) 2012-01-05 US disclosed
US-7947174-B2 Sol-gel monolithic column with optical window and method of making UNIVERSITY OF SOUTH FLORIDA (US) 2011-05-24 US disclosed
US-7749607-B2 Film derrived from a conductive sol-gel aqueous emulsion containing emulsifiers, organofunctional silanes, and conductive metals and/or metal oxides; mirror finish smooth surface; powder coating for heat sensitive and/or flammable objects NORTHERN ILLINOIS UNIVERSITY (US) 2010-07-06 US disclosed
US-20100112208-A1 Titania-Based Coating for Capillary Microextraction MALIK ABDUL 2010-05-06 US disclosed
US-7622191-B2 also called in tube solid-phase microextraction; inorganic-organic hybrid coating of titania-polydimethylsiloxane; preconcentrates sample for high pressure liquid chromatography analysis; pH stability, retains extraction performance even after NaOH treatment UNIVERSITY OF SOUTH FLORIDA (US) 2009-11-24 US disclosed
US-20090189129-A1 Film derrived from a conductive sol-gel aqueous emulsion containing emulsifiers, organofunctional silanes, and conductive metals and/or metal oxides; mirror finish smooth surface; powder coating for heat sensitive and/or flammable objects NORTHERN ILLINOIS UNIVERSITY 2009-07-30 US disclosed
US-7534831-B2 Mixtures of water, emulsifiers, organic silicon compounds, electroconductive metals/metal oxide particles and pH controllers, used to form films that improve electrical properties of wood fibers or plastics NORTHERN ILLINOIS UNIVERSITY (US) 2009-05-19 US disclosed
WO-2001058562-A1 SOL-GEL MONOLITHIC COLUMN WITH OPTICAL WINDOW AND METHOD OF MAKING UNIVERSITY OF SOUTH FLORIDA (US) 2001-08-16 WO disclosed
US-6086743-A Adhesion enhancement for metal foil GOULD ELECTRONICS, INC. (US) 2000-07-11 US disclosed
EP-0987286-A2 Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-03-22 EP disclosed
EP-0974685-A1 Metal foil with improved bonding to substrates and method for making said foil Gould Electronics Inc. (US) 2000-01-26 EP disclosed
US-6013705-A Silicone gels and composites from sheet and tube organofunctional siloxane polymers DOW CORNING CORPORATION (US) 2000-01-11 US disclosed
US-5908542-A CONTACTING A METAL FOIL WITH AN ACIDIC SOLUTION; PLACING THE METAL FOIL IN A NICKEL TREATMENT BATH AND APPLYING A CURRENT THROUGH THE NICKEL TREATMENT BATH, WHEREIN THE NICKEL TREATMENT BATH CONTAINS AT LEAST ABOUT TWO PLATING ZONES, GOULD ELECTRONICS INC. (US) 1999-06-01 US disclosed
US-5885436-A Adhesion enhancement for metal foil GOULD ELECTRONICS INC. (US) 1999-03-23 US disclosed
EP-0896502-A1 Method of treating metal foil for enhancing adhesion Gould Electronics Inc. (US) 1999-02-10 EP disclosed