Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 4/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 7/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21296842 | 0.89 | BRAF (0.49) | ACKR3BRAFWNT1GSK3BDYRK1A | |
| SCHEMBL21296779 | 0.84 | JAK2 (0.43) | JAK2JAK3 | |
| SCHEMBL21296774 | 0.76 | MAPT (0.46) | JAK2JAK3 | |
| SCHEMBL21296781 | 0.75 | MAPT (0.47) | BRAF | |
| SCHEMBL21296800 | 0.73 | CNR1 (0.43) | BRAF | |
| SCHEMBL21296839 | 0.72 | PDK1 (0.48) | JAK2 | |
| SCHEMBL23610573 | 0.71 | SCN3A (0.44) | BRAF | |
| SCHEMBL21296771 | 0.71 | MAP2K4 (0.39) | CDK5CDK5R1DYRK1A | |
| SCHEMBL23610577 | 0.71 | HSD17B1 (0.47) | BRAF | |
| SCHEMBL21296776 | 0.69 | KMT2A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165158-A1 | IL-6 INHIBITORS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-08-29 | — | — | WO | disclosed |