SCHEMBL21296876

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23001720	0.90	MAPT (0.50)	CASP3KDM4EALDH1A1MAPTHTT
	SCHEMBL21296870	0.88	KDM4E (0.51)	KDM4EALDH1A1MAPTHTTSMN1; SMN2
	SCHEMBL22795376	0.88	ALDH1A1 (0.43)	CASP3ALOX5LMNATSHRMAPK1
	SCHEMBL21296874	0.81	AKR1C3 (0.41)	LMNAKDM4EMAPTSMN1; SMN2NPC1
	SCHEMBL31144590	0.80	ALDH1A1 (0.46)	ALOX5LMNAKDM4EALDH1A1MAPT
	SCHEMBL23002061	0.80	ALDH1A1 (0.46)	ALOX5LMNAKDM4EALDH1A1MAPT
	SCHEMBL23002100	0.79	HAO1 (0.51)	CASP3ALDH1A1MAPTHTTILK
	SCHEMBL11340551	0.78	SMN1; SMN2 (0.50)	CASP3ALOX5KDM4EALDH1A1MAPT
	SCHEMBL9644563	0.71	RAB9A (0.63)	CASP3LMNATSHRKDM4EALDH1A1
	SCHEMBL23025720	0.71	PDE4D (0.50)	LMNATSHRKDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.