Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7277080 | 0.83 | PDE4D (0.44) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL5648877 | 0.83 | KDM4E (0.46) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL1928112 | 0.83 | PDE4D (0.44) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL7764111 | 0.82 | LMNA (0.48) | KDM4EPOLBMAPTTSHRALDH1A1 | |
| SCHEMBL5906562 | 0.81 | PDE4D (0.43) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL11368014 | 0.81 | ALDH1A1 (0.50) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL15897055 | 0.81 | PDE4D (0.43) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL1412491 | 0.80 | PDE4D (0.42) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL5648880 | 0.80 | KDM4E (0.47) | PDE4DKDM4EPOLBCYP1A2MEN1 | |
| SCHEMBL11528604 | 0.80 | PDE4D (0.42) | PDE4DKDM4EPOLBCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025124460-A1 | TRICYCLIC FUSED HETEROCYCLIC PDE3/4 DUAL INHIBITOR, AND PREPARATION AND USE THEREFOR | 石家庄以岭药业股份有限公司 | 2025-06-19 | — | — | WO | disclosed |
| WO-2021035196-A1 | COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES | OXALURX, INC. (US) | 2021-02-25 | — | — | WO | disclosed |