SCHEMBL21296913

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21296963	0.91	HAO1 (0.49)	HAO1CDH1CTNNB1TCF7L2ALPL
	SCHEMBL21312624	0.89	HAO1 (0.47)	HAO1PRKAG1PRKAA1PRKAB1PTPN1
	SCHEMBL21296934	0.86	RXRA (0.46)	RXRARXRBHAO1MCL1BCL2L1
	SCHEMBL29799196	0.86	RXRA (0.46)	RXRARXRBHAO1MCL1BCL2L1
	SCHEMBL21296890	0.86	HAO1 (0.52)	HAO1CDH1CTNNB1TCF7L2ALPL
	SCHEMBL21296872	0.86	HAO1 (0.44)	HAO1MCL1BCL2L1PRKAG1PRKAA1
	SCHEMBL24154378	0.85	KMO (0.41)	HAO1CDH1CTNNB1TCF7L2PRKAG1
	SCHEMBL21296854	0.85	HAO1 (0.44)	HAO1MCL1PRKAG1PRKAA1PRKAB1
	SCHEMBL21312672	0.84	HAO1 (0.41)	HAO1MCL1PRKAG1PRKAA1PRKAB1
	SCHEMBL25465250	0.83	PRKAG1 (0.39)	HAO1MCL1PRKAG1PRKAA1PRKAB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.