Catechol

Catechol

SCHEMBL21296992

CC(=O)CC(C)=O.Oc1ccccc1O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.53
ALDH1A1 P00352 5/20 0.53
MAPT P10636 4/20 0.53
HIF1A Q16665 4/20 0.53
LMNA P02545 3/20 0.53
CA12 O43570 3/20 0.53
CA2 P00918 3/20 0.53
CA14 Q9ULX7 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
HPGD P15428 2/20 0.53
CA4 P22748 2/20 0.53
NFKB1 P19838 2/20 0.53
HSD17B10 Q99714 2/20 0.53
NPC1 O15118 1/20 0.53
GMNN O75496 1/20 0.53
EGFR P00533 1/20 0.53
FYN P06241 1/20 0.53
POLB P06746 1/20 0.53
CA3 P07451 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Catechol SCHEMBL27321263 0.84 ALDH1A1 (0.53) KDM4EALDH1A1MAPTHIF1ALMNA
Catechol SCHEMBL2555536 0.83 KDM4E (0.67) KDM4EALDH1A1MAPTHIF1ALMNA
Catechol SCHEMBL28163142 0.83 KMT2A (0.61) KDM4EALDH1A1MAPTHIF1ALMNA
Salicyladehyde SCHEMBL10953961 0.81 TRIM24 (0.69) KDM4EALDH1A1MAPTLMNACA12
Catechol SCHEMBL10659163 0.80 KDM4E (0.62) KDM4EALDH1A1MAPTHIF1ALMNA
Catechol SCHEMBL2707627 0.80 CA2 (0.62) KDM4EALDH1A1MAPTHIF1ALMNA
Catechol SCHEMBL8411371 0.80 CA2 (0.62) KDM4EALDH1A1MAPTHIF1ALMNA
SCHEMBL31589529 0.80 MEN1 (0.56) KDM4EALDH1A1MAPTHIF1ALMNA
SCHEMBL2240149 0.80 MEN1 (0.56) KDM4EALDH1A1MAPTHIF1ALMNA
Biphenyl SCHEMBL27660096 0.79 MAPT (0.56) KDM4EALDH1A1MAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019165425-A1 ANTIMICROBIAL GALLIUM COMPOUNDS AND METHODS THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2019-08-29 WO disclosed