Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Catechol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | CA12 | O43570 | 4/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | CA4 | P22748 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | FYN | P06241 | 2/20 | 0.62 |
| ▸ | GMNN | O75496 | 1/20 | 0.62 |
| ▸ | EGFR | P00533 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL2707627 | 1.00 | CA2 (0.62) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL27477125 | 0.97 | CA2 (0.59) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL28266919 | 0.92 | CA2 (0.53) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL2555536 | 0.90 | KDM4E (0.67) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL4622850 | 0.88 | CA2 (0.56) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL10659163 | 0.88 | KDM4E (0.62) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL27240704 | 0.87 | MAPT (0.48) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL154583 | 0.87 | ALDH1A1 (0.71) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL30530338 | 0.87 | ALDH1A1 (0.71) | CA2ALDH1A1HPGDCA12CA14 | |
| Catechol SCHEMBL21196902 | 0.87 | ALDH1A1 (0.71) | CA2ALDH1A1HPGDCA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965460-A | Polyurethane composition with (meth)acrylate end groups useful in the manufacture of polishing pads | MAC DERMID, INCORPORATED (US) | 1999-10-12 | — | — | US | claimed |
| US-9643285-B2 | Cream solder composition | FUJI ELECTRIC CO., LTD. (JP) | 2017-05-09 | — | — | US | disclosed |
| US-20150044465-A1 | FLUX FOR RESIN CORED SOLDER AND RESIN CORED SOLDER | FUJI ELECTRIC CO., LTD. (JP) | 2015-02-12 | — | — | US | disclosed |
| US-20150020923-A1 | SOLDERING FLUX AND SOLDER COMPOSITION | FUJI ELECTRIC FA COMPONENTS & SYSTEMS CO., LTD. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-5965460-A | Polyurethane composition with (meth)acrylate end groups useful in the manufacture of polishing pads | MAC DERMID, INCORPORATED (US) | 1999-10-12 | — | — | US | disclosed |