Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | CA2 | P00918 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 4/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | CA4 | P22748 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
| ▸ | FYN | P06241 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CA3 | P07451 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL10659163 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL2707627 | 0.90 | CA2 (0.62) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL8411371 | 0.90 | CA2 (0.62) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL27612050 | 0.88 | MAPT (0.59) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL27477125 | 0.88 | CA2 (0.59) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL6611011 | 0.85 | KDM4E (0.58) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL4622850 | 0.85 | CA2 (0.56) | KDM4EALDH1A1CA2HPGDMAPT | |
| Orthocresol SCHEMBL18725587 | 0.83 | TRPA1 (0.50) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL8381469 | 0.83 | ALDH1A1 (0.53) | KDM4EALDH1A1CA2HPGDMAPT | |
| Catechol SCHEMBL21296992 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1CA2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020191329-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-24 | — | — | WO | disclosed |
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-24 | — | — | US | disclosed |
| WO-2019178547-A1 | BENZOXAZINE POLYMERS AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-19 | — | — | WO | disclosed |
| CN-110156582-A | A kind of preparation method of high-purity phloretin | 苏州禾研生物技术有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-109939055-A | A kind of anti-oxidant cosmetic composition of duration | 上海科颜生物科技有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-106366723-B | A kind of waterborne flame retardant adhesive for the type of resistance to burn-through of weaving | 嘉兴市新加新化工有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-105543108-B | Purple stain mould QL-9204 and conversion phloridzin prepare the application in phloretin | 浙江工业大学 | 2019-03-05 | — | — | CN | disclosed |
| CN-109355317-A | A method of phloridzin is converted into phloretin | 桂林莱茵生物科技股份有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-109180628-A | A kind of preparation method of apiolin | 陕西嘉禾生物科技股份有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-106366723-A | Burnthrough-resistant water-based fire retardant glue for spinning | 嘉兴市新加新化工有限公司 | 2017-02-01 | — | — | CN | disclosed |
| CN-105543108-A | Penicillium purpurescens QL-9204 and application for preparing phloretin during phlorizin conversion | UNIV ZHEJIANG TECHNOLOGY | 2016-05-04 | — | — | CN | disclosed |
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |
| WO-2011127301-A2 | COVALENT ORGANIC FRAMEWORKS AND METHODS OF MAKING SAME | CORNELL UNIVERSITY (US) | 2011-10-13 | — | — | WO | disclosed |
| US-20030134824-A1 | Beta-cyclodextrin dimers and phthalocyanines and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-07-17 | — | — | US | disclosed |
| WO-2003052060-A2 | BETA-CYCLODEXTRIN DIMERS AND PHTHALOCYANINES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134824-A1 | Beta-cyclodextrin dimers and phthalocyanines and uses thereof | CRY2, CRY1, HCCS | KDM4E 4432/4885ALDH1A1 2009/4885CA2 94/4885 |
| US-20200298194-A1 | ARAMID AMPHIPHILE SELF-ASSEMBLED NANOSTRUCTURES | ANXA6, ANXA1, ANXA11 | KDM4E 4448/4885ALDH1A1 3690/4885CA2 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.