SCHEMBL21297913

SCHEMBL21297913

c1ccc2c(c1)ccc1c3ncccc3c3nccnc3c21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.48
MAPT P10636 5/20 0.48
CCR1 P32246 4/20 0.48
CCR8 P51685 4/20 0.48
LMNA P02545 3/20 0.48
KDM4E B2RXH2 3/20 0.48
TSHR P16473 3/20 0.48
CCR5 P51681 2/20 0.48
HSP90AA1 P07900 2/20 0.48
TP53 P04637 2/20 0.48
PMP22 Q01453 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HIF1A Q16665 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
GMNN O75496 1/20 0.48
MMP2 P08253 1/20 0.48
CYP2D6 P10635 1/20 0.48
MMP9 P14780 1/20 0.48
ALOX15 P16050 1/20 0.48
NFKB1 P19838 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21298459 0.94 MAPT (0.50) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21297915 0.92 HPRT1 (0.44) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21297911 0.91 CYP3A4 (0.47) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21297774 0.91 HPRT1 (0.43) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21791177 0.91 MAPT (0.50) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21298464 0.91 CYP3A4 (0.50) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21298441 0.89 CYP3A4 (0.52) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21297766 0.88 HPRT1 (0.48) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL21298450 0.88 HPRT1 (0.48) CYP3A4MAPTCCR1CCR8LMNA
SCHEMBL29389665 0.88 HPRT1 (0.48) CYP3A4MAPTCCR1CCR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-12-01 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS CYP3A4 2938/4885MAPT 467/4885CCR1 3636/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS CYP3A4 2938/4885MAPT 467/4885CCR1 3636/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS CYP3A4 2938/4885MAPT 467/4885CCR1 3636/4885
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials KCNK4, TRPC4, TBRG4 CYP3A4 34/4885MAPT 1680/4885CCR1 4648/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK CYP3A4 320/4885MAPT 2286/4885CCR1 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.