Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16057480 | 0.72 | PARP11 (0.42) | PARP1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL6124108 | 0.72 | PARP1 (0.62) | PARP1PARP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL794250 | 0.71 | PARP11 (0.44) | PARP1GAAKMT2AMEN1MAPK1 | |
| SCHEMBL699630 | 0.64 | NPC1 (0.40) | PARP1ALDH1A1PKN1PKN2TNKS2 | |
| SCHEMBL30124040 | 0.63 | NOS2 (0.40) | PARP1ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL106149 | 0.61 | LRRK2 (0.50) | PARP1PARP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29380714 | 0.61 | LRRK2 (0.50) | PARP1PARP2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL23225430 | 0.60 | PARP1 (0.39) | PARP1PARP2KDM4EKMT2AMEN1 | |
| SCHEMBL12326317 | 0.59 | PARP10 (0.38) | PARP1ALDH1A1KDM4EPKN1PKN2 | |
| SCHEMBL14251056 | 0.58 | NOS1 (0.49) | PARP1PARP2KDM4EPKN1PKN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10391181-B2 | Cyclodextrin and antibody-drug conjugate formulations | SEATTLE GENETICS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10391181-B2 | Cyclodextrin and antibody-drug conjugate formulations | CDR2, GABRA6, GABRA4 | PARP1 4245/4885PARP2 4398/4885ALDH1A1 610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.