Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17400676 | 1.00 | CRHR1 (0.40) | CRHR1ACHETRPV4KDM1APDE10A | |
| SCHEMBL21301035 | 0.90 | CRHR1 (0.44) | CRHR1ACHETRPV4KDM1APDE10A | |
| SCHEMBL17412696 | 0.89 | TRPV4 (0.43) | CRHR1ACHETRPV4SLC2A1KDM4E | |
| SCHEMBL18724238 | 0.88 | CRHR1 (0.43) | CRHR1ACHESLC2A1HRH3ALDH1A1 | |
| SCHEMBL18724017 | 0.88 | MAP4K4 (0.38) | CRHR1ACHETRPV4SLC2A1HRH3 | |
| SCHEMBL17400621 | 0.88 | CRHR1 (0.43) | CRHR1ACHESLC2A1HRH3ALDH1A1 | |
| SCHEMBL21301145 | 0.87 | RORB (0.39) | CRHR1ACHEKDM1APDE10AHRH3 | |
| SCHEMBL17412800 | 0.87 | RORB (0.39) | CRHR1ACHEKDM1APDE10AHRH3 | |
| SCHEMBL18724139 | 0.86 | CRHR1 (0.40) | CRHR1HRH3KDM4EALDH1A1MAPT | |
| SCHEMBL18724315 | 0.85 | CCR2 (0.36) | CRHR1TRPV4SLC2A1HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963036-B1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE AND SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2019-08-28 | — | — | EP | disclosed |