Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 11/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005887 | 0.93 | CRHR1 (0.38) | CRHR1CTSSSPHK2MPLS1PR4 | |
| SCHEMBL18724210 | 0.90 | MAPK1 (0.42) | CRHR1CTSSMPLS1PR1MAPK1 | |
| SCHEMBL21006251 | 0.85 | PDE3B (0.40) | CTSSSPHK2MPLS1PR4S1PR1 | |
| SCHEMBL18724292 | 0.83 | CTSS (0.39) | CRHR1CTSSMPLS1PR1CTSK | |
| SCHEMBL21301073 | 0.81 | MAPK1 (0.43) | CRHR1S1PR1MAPK1ALDH1A1CRHBP | |
| SCHEMBL19123486 | 0.81 | SPHK2 (0.40) | CTSSSPHK2MPLS1PR4S1PR1 | |
| SCHEMBL17400488 | 0.81 | MPL (0.49) | MPLS1PR1 | |
| SCHEMBL18724169 | 0.81 | MAPT (0.39) | CRHR1CTSSS1PR1CRHBPCRHR2 | |
| SCHEMBL21301163 | 0.80 | NOTUM (0.40) | CRHR1MPLS1PR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17400684 | 0.80 | MPL (0.42) | CRHR1MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963036-B1 | 2-ACYLAMINOTHIAZOLE DERIVATIVE AND SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2019-08-28 | — | — | EP | disclosed |