SCHEMBL2130786

SCHEMBL2130786

C=Cc1cccc(CCl)c1CCl

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950753 0.86 ALDH1A1 (0.36) ALDH1A1GABRA1GABRB2
SCHEMBL28379576 0.83 ALDH1A1 (0.38) ALDH1A1
SCHEMBL9413121 0.82 ALDH1A1 (0.39) ALDH1A1TSHR
SCHEMBL15850 0.80 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL29395089 0.80 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL6859831 0.79 THRA (0.40)
SCHEMBL4450030 0.79 ALDH1A1 (0.40) ALDH1A1GABRA1GABRB2TSHR
SCHEMBL810324 0.79 ALDH1A1 (0.45) ALDH1A1GABRA1GABRB2TSHR
SCHEMBL9635025 0.78 ALDH1A1 (0.48) ALDH1A1TSHR
Ammonia Solution, Strong SCHEMBL3755399 0.78 ALDH1A1 (0.48) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4192920-A Uniform polymer beads and ion exchange resins therefrom prepared by post-crosslinking of lightly crosslinked beads ROHM AND HAAS COMPANY (US) 1980-03-11 US claimed
US-4191814-A POLYCHLOROMETHYLSTYRENE, POLY-TERT-AMINE ROHM AND HAAS COMPANY (US) 1980-03-04 US claimed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US claimed
CN-106661309-B Composition for thermoplastic elastomer 株式会社可乐丽 2019-04-16 CN disclosed
CN-106715576-B Composition for thermoplastic elastomer and molded product 株式会社可乐丽 2019-04-16 CN disclosed
EP-2450348-B1 NOVEL DIARYLAMINE COMPOUND, AND ANTI-AGING AGENT, POLYMER COMPOSITION, CROSSLINKED RUBBER PRODUCT AND MOLDED ARTICLE THEREOF, AND METHOD FOR PRODUCING DIARYLAMINE COMPOUND ZEON CORP (JP) 2016-12-14 EP disclosed
US-8883888-B2 Diarylamine compounds, aging inhibitor, polymer composition, crosslinked rubber product and molded article of the crosslinked product, and method of producing diarylamine compound ZEON CORPORATION (JP) 2014-11-11 US disclosed
EP-2450348-A1 NOVEL DIARYLAMINE COMPOUND, AND ANTI-AGING AGENT, POLYMER COMPOSITION, CROSSLINKED RUBBER PRODUCT AND MOLDED ARTICLE THEREOF, AND METHOD FOR PRODUCING DIARYLAMINE COMPOUND Zeon Corporation (JP) 2012-05-09 EP disclosed
US-20120101196-A1 NOVEL DIARYLAMINE COMPOUNDS, AGING INHIBITOR, POLYMER COMPOSITION, CROSSLINKED RUBBER PRODUCT AND MOLDED ARTICLE OF THE CROSSLINKED PRODUCT, AND METHOD OF PRODUCING DIARYLAMINE COMPOUND ZEON CORPORATION (JP) 2012-04-26 US disclosed
EP-1550694-B1 ACRYLIC RUBBER COMPOSITION AND CROSSLINKED OBJECT ZEON CORP (JP) 2010-09-08 EP disclosed
US-7459495-B2 Acrylic rubber composition and crosslinked object ZEON CORPORATION (JP) 2008-12-02 US disclosed
US-4535054-A IRRADIATION TO GIVE NEGATIVE PATTERN IMAGE, DEVELOPMENT BY DISSOLUING UNEXPOSED POLYMER WITH SOLVENT AND RINSING HUGHES AIRCRAFT COMPANY (US) 1985-08-13 US disclosed
US-4373031-A Synthesis of anion exchange polymers employing ditertiary amines IONICS, INCORPORATED (US) 1983-02-08 US disclosed
US-4273878-A SUSPENSION POLYMERIZED POLY(CHLOROMETHYLSTYRENE), AMINATION-QUATERNIZATION, UNIFORM BEADS ROHM AND HAAS COMPANY (US) 1981-06-16 US disclosed
US-4192920-A Uniform polymer beads and ion exchange resins therefrom prepared by post-crosslinking of lightly crosslinked beads ROHM AND HAAS COMPANY (US) 1980-03-11 US disclosed
US-4192920-A Uniform polymer beads and ion exchange resins therefrom prepared by post-crosslinking of lightly crosslinked beads ROHM AND HAAS COMPANY (US) 1980-03-11 US disclosed
US-4191814-A POLYCHLOROMETHYLSTYRENE, POLY-TERT-AMINE ROHM AND HAAS COMPANY (US) 1980-03-04 US disclosed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4093567-A Aminated crosslinked copolymers of bis(chloromethyl) styrene which exhibit improved anion exchange properties ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120101196-A1 NOVEL DIARYLAMINE COMPOUNDS, AGING INHIBITOR, POLYMER COMPOSITION, CROSSLINKED RUBBER PRODUCT AND MOLDED ARTICLE OF THE CROSSLINKED PRODUCT, AND METHOD OF PRODUCING DIARYLAMINE COMPOUND CDKN1A, DDAH1, CCNI ALDH1A1 849/4885GABRA1 4532/4885GABRB2 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.