SCHEMBL4450030

SCHEMBL4450030

C=Cc1cccc(CCl)c1C=C

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL11331288 0.93 ALDH1A1 (0.35) ALDH1A1
Trimethylammonium SCHEMBL18816318 0.93 ALDH1A1 (0.35) ALDH1A1
SCHEMBL8449526 0.87 GABRA1 (0.34) ALDH1A1GABRA1GABRB2TSHR
SCHEMBL420437 0.81 GABRA1 (0.43) ALDH1A1GABRA1GABRB2
SCHEMBL15850 0.80 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL29395089 0.80 ALDH1A1 (0.50) ALDH1A1TSHR
SCHEMBL810324 0.79 ALDH1A1 (0.45) ALDH1A1GABRA1GABRB2TSHR
SCHEMBL9311388 0.79 PNMT (0.39) ALDH1A1GABRA1GABRB2
SCHEMBL1123438 0.79 GABRA1 (0.47) ALDH1A1GABRA1GABRB2
SCHEMBL2130786 0.79 ALDH1A1 (0.40) ALDH1A1GABRA1GABRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1789423-B1 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-04-13 EP claimed
US-7531588-B2 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-05-12 US claimed
EP-1789423-A2 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME General Electric Company (US) 2007-05-30 EP claimed
US-20060281841-A1 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-12-14 US claimed
WO-2006015010-A2 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME GENERAL ELECTRIC COMPAMY (US) 2006-02-09 WO claimed
US-20060025506-A1 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-02-02 US claimed
EP-1789423-B1 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2016-04-13 EP disclosed
CN-103122044-B Sulphonic acid type macroporous ion exchange resin and preparation method thereof CHINA PETROLEUM & CHEMICAL 2015-05-13 CN disclosed
CN-103122043-B Preparation method of deiodination agent CHINA PETROLEUM & CHEMICAL 2015-04-08 CN disclosed
CN-103121934-B Method for reducing iodide impurity content in acetic acid CHINA PETROLEUM & CHEMICAL 2014-07-23 CN disclosed
CN-103121934-A Method for reducing iodide impurity content in acetic acid CHINA PETROLEUM & CHEMICAL 2013-05-29 CN disclosed
CN-103122044-A Sulphonic acid type macroporous ion exchange resin and preparation method thereof CHINA PETROLEUM & CHEMICAL 2013-05-29 CN disclosed
CN-103122043-A Preparation method of deiodination agent CHINA PETROLEUM & CHEMICAL 2013-05-29 CN disclosed
EP-1789423-A2 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME General Electric Company (US) 2007-05-30 EP disclosed
US-20060281841-A1 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-12-14 US disclosed
WO-2006015010-A2 SILANE COMPOSITIONS, PROCESSES FOR THEIR PREPARATION AND RUBBER COMPOSITIONS CONTAINING SAME GENERAL ELECTRIC COMPAMY (US) 2006-02-09 WO disclosed
US-20060025506-A1 Silane compositions, processes for their preparation and rubber compositions containing same MOMENTIVE PERFORMANCE MATERIALS INC. 2006-02-02 US disclosed
US-4686149-A CORONA DISCHARGE TREATMENT, COATING WITH HYDROPHOBIC POLYMER, AND IRRADIATION FUJI PHOTO FILM CO., LTD. (JP) 1987-08-11 US disclosed
US-4213831-A Aluminum container for processing vinylbenzyl chlorides THE DOW CHEMICAL COMPANY (US) 1980-07-22 US disclosed
US-4147548-A Photographic element comprising quaternary nitrogen polymeric mordant FUJI PHOTO FILM CO., LTD. (JP) 1979-04-03 US disclosed