Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.57 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 10/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 4/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.50 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7451652 | 0.84 | MAPT (0.68) | ALDH1A1HPGDMAPTHSD11B1MGLL | |
| SCHEMBL4220849 | 0.83 | GRM5 (0.65) | GRM5GRM3L3MBTL3L3MBTL1NAMPT | |
| SCHEMBL3638834 | 0.83 | GRM5 (0.65) | GRM5GRM3L3MBTL3L3MBTL1NAMPT | |
| SCHEMBL6223960 | 0.82 | HPGD (0.70) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL23884758 | 0.81 | MGLL (0.46) | GRM5L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL1471431 | 0.81 | L3MBTL3 (0.51) | GRM5L3MBTL3L3MBTL1MBTD1HSP90AA1 | |
| SCHEMBL23884815 | 0.81 | GRM3 (0.56) | GRM3L3MBTL3L3MBTL1ALDH1A1HPGD | |
| SCHEMBL20645608 | 0.81 | HPGD (0.50) | GRM3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL25167976 | 0.81 | GRM3 (0.56) | GRM3L3MBTL3L3MBTL1ALDH1A1HPGD | |
| SCHEMBL6617073 | 0.81 | HPGD (0.74) | L3MBTL3L3MBTL1MBTD1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | GRM5 1315/4885GRM3 2038/4885L3MBTL3 606/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | GRM5 1156/4885GRM3 2135/4885L3MBTL3 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.