Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21311159 | 0.81 | HTT (0.46) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20097049 | 0.80 | ADORA3 (0.51) | HTTSMN1; SMN2TP53PAX8LMNA | |
| SCHEMBL21311392 | 0.78 | DOT1L (0.45) | ADORA2ADOT1LPI4KAPI4K2BPI4K2A | |
| SCHEMBL21311157 | 0.78 | PI4KA (0.41) | ADORA3ADORA2AADORA1DOT1LPI4KA | |
| SCHEMBL21311391 | 0.77 | ADORA2A (0.43) | ADORA3ADORA2AADORA1DOT1LPI4KA | |
| SCHEMBL21311156 | 0.77 | ADORA2A (0.40) | ADORA3ADORA2AADORA1DOT1LPI4KA | |
| SCHEMBL21311397 | 0.76 | DOT1L (0.43) | ADORA2ADOT1LPI4KAPI4K2BPI4K2A | |
| SCHEMBL20097018 | 0.72 | ADORA3 (0.70) | SMN1; SMN2TP53PAX8LMNAADORA3 | |
| SCHEMBL31711721 | 0.69 | HTT (0.75) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20097160 | 0.64 | CCNB2 (0.69) | HTTCCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | HTT 2424/4885CCNB2 4302/4885CDK1 4187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.