Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.57 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.50 |
| ▸ | PI4KA | P42356 | 2/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | NSD3 | Q9BZ95 | 5/20 | 0.45 |
| ▸ | NSD2 | O96028 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14822332 | 0.82 | ADORA2A (0.61) | FGFR1SLC22A6ADORA2AADORA1PI4KA | |
| SCHEMBL11247503 | 0.81 | ENPP1 (0.60) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL15214233 | 0.80 | ADORA2A (0.63) | FGFR1SLC22A6ADORA2AADORA1PI4KA | |
| SCHEMBL2293269 | 0.80 | ADORA2A (0.66) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL10566016 | 0.80 | ENPP1 (0.59) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL20096689 | 0.80 | ADORA2A (0.66) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL25306268 | 0.79 | ENPP1 (0.61) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL29385353 | 0.77 | ADORA2A (0.57) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL18786971 | 0.77 | ADORA2A (0.57) | ENPP1FGFR1SLC22A6NT5EADORA2A | |
| SCHEMBL8561474 | 0.77 | ENPP1 (0.73) | ENPP1FGFR1SLC22A6NT5EADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | ENPP1 980/4885FGFR1 4576/4885SLC22A6 4494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.