Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 4/20 | 0.63 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683371 | 0.90 | AGTR2 (0.78) | AGTR2AGTR1 | |
| SCHEMBL2927273 | 0.89 | AGTR2 (0.77) | AGTR2AGTR1 | |
| Potassium SCHEMBL3033376 | 0.89 | AGTR2 (0.77) | AGTR2AGTR1 | |
| Azilsartan Medoxomil SCHEMBL2129551 | 0.88 | AGTR2 (0.81) | AGTR2AGTR1ABCC3ABCC4ABCB11 | |
| SCHEMBL7011057 | 0.86 | AGTR1 (0.46) | AGTR2AGTR1 | |
| SCHEMBL10298805 | 0.86 | AGTR2 (0.57) | AGTR2AGTR1ABCC3ABCC4ABCB11 | |
| Potassium Ion SCHEMBL2927275 | 0.85 | AGTR2 (0.58) | AGTR2AGTR1ABCC3ABCC4ABCB11 | |
| Potassium Ion SCHEMBL2926518 | 0.84 | AGTR2 (0.57) | AGTR2AGTR1ABCC3ABCC4ABCB11 | |
| SCHEMBL2844345 | 0.83 | AGTR1 (0.48) | AGTR2AGTR1 | |
| SCHEMBL5548451 | 0.83 | AGTR2 (0.67) | AGTR2AGTR1ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2068812-B9 | MEDICINAL PACKAGE | TAKEDA PHARMACEUTICAL (JP) | 2012-08-08 | — | — | EP | disclosed |
| US-20120100093-A1 | MEDICINAL PACKAGE | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2012-04-26 | — | — | US | disclosed |
| US-20090308780-A1 | Medicinal package | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-12-17 | — | — | US | disclosed |