Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | USP8 | P40818 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21323152 | 0.83 | ALDH1A1 (0.57) | NAMPTALDH1A1LMNAERAP1KDM4E | |
| SCHEMBL19921880 | 0.78 | NAMPT (0.53) | NAMPTALDH1A1LMNAERAP1KMT2A | |
| SCHEMBL21322825 | 0.70 | KDR (0.55) | ALDH1A1LMNAKMT2AKDM4EMAPT | |
| SCHEMBL25140639 | 0.70 | USP2 (0.66) | KMT2ATSHRUSP2USP8CKS1B | |
| SCHEMBL19848269 | 0.70 | KMT2A (0.60) | NAMPTKMT2ATSHRUSP2USP8 | |
| SCHEMBL15310953 | 0.69 | NAMPT (1.00) | NAMPT | |
| SCHEMBL23877565 | 0.67 | USP2 (0.59) | NAMPTKMT2ATSHRUSP2USP8 | |
| SCHEMBL30547616 | 0.67 | USP2 (0.59) | NAMPTKMT2ATSHRUSP2USP8 | |
| SCHEMBL21324442 | 0.66 | NAMPT (0.86) | NAMPT | |
| SCHEMBL165379 | 0.66 | NAMPT (1.00) | NAMPTALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533470-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | Kyoto University (JP) | 2019-09-04 | — | — | EP | disclosed |