Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | USP8 | P40818 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CCR9 | P51686 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932362 | 0.89 | ALDH1A1 (0.64) | NAMPTLMNAALDH1A1KMT2AERAP1 | |
| SCHEMBL20117834 | 0.89 | ALDH1A1 (0.64) | NAMPTLMNAALDH1A1KMT2AERAP1 | |
| SCHEMBL19932327 | 0.89 | ALDH1A1 (0.64) | NAMPTLMNAALDH1A1KMT2AERAP1 | |
| SCHEMBL22111910 | 0.85 | NAMPT (0.48) | NAMPTLMNAALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL19932398 | 0.84 | LMNA (0.53) | NAMPTLMNAALDH1A1ERAP1KDM4E | |
| SCHEMBL19921882 | 0.84 | LMNA (0.53) | NAMPTLMNAALDH1A1ERAP1KDM4E | |
| SCHEMBL20117643 | 0.83 | LMNA (0.57) | NAMPTLMNAALDH1A1ERAP1KDM4E | |
| SCHEMBL20117914 | 0.83 | LMNA (0.52) | NAMPTLMNAALDH1A1ERAP1KDM4E | |
| SCHEMBL21323075 | 0.83 | LMNA (0.52) | NAMPTLMNAALDH1A1ERAP1KDM4E | |
| SCHEMBL19921881 | 0.83 | LMNA (0.66) | NAMPTLMNAALDH1A1KMT2AERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200188382-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | KYOTO UNIVERSITY (JP) | 2020-06-18 | — | — | US | disclosed |
| US-20200188382-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | KYOTO UNIVERSITY (JP) | 2020-06-18 | — | — | US | disclosed |
| EP-3533470-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | Kyoto University (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-20180290979-A1 | COMPOSITION HAVING COMPOUND ACCELERATING PHOSPHORYLATION OF AMPK AS EFFECTIVE COMPONENT | KYOTO UNIVERSITY (JP) | 2018-10-11 | — | — | US | disclosed |
| WO-2018079855-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | 国立大学法人京都大学 | 2018-05-03 | — | — | WO | disclosed |
| EP-3289873-A1 | COMPOSITION HAVING COMPOUND ACCELERATING PHOSPHORYLATION OF AMPK AS EFFECTIVE COMPONENT | Kyoto University (JP) | 2018-03-07 | — | — | EP | disclosed |
| EP-3289873-A1 | COMPOSITION HAVING COMPOUND ACCELERATING PHOSPHORYLATION OF AMPK AS EFFECTIVE COMPONENT | Kyoto University (JP) | 2018-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200188382-A1 | PHARMACEUTICAL COMPOSITION FOR INDUCING PROGRAMMED CELL DEATH IN CANCER CELLS | CASP3, BAX, BAD | NAMPT 437/4885LMNA 1177/4885ALDH1A1 2235/4885 |
| US-20180290979-A1 | COMPOSITION HAVING COMPOUND ACCELERATING PHOSPHORYLATION OF AMPK AS EFFECTIVE COMPONENT | PRKAG1, PRKAG2, PRKAB1 | NAMPT 762/4885LMNA 1405/4885ALDH1A1 2830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.