Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413853 | 0.83 | SRD5A1 (0.49) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL323547 | 0.80 | XDH (0.54) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| Hydrogen Sulfide SCHEMBL6721312 | 0.78 | XDH (0.52) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL4012043 | 0.78 | GABRA1 (0.52) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL10358540 | 0.76 | GABRA1 (0.46) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL6013229 | 0.74 | GABRA1 (0.52) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL6398012 | 0.74 | SRD5A1 (0.49) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL3957273 | 0.73 | SRD5A1 (0.45) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL9754486 | 0.73 | GABRA1 (0.43) | SRD5A1XDHGABRA1GABRB2ALDH1A1 | |
| SCHEMBL13030493 | 0.72 | SRD5A1 (0.44) | SRD5A1XDHGABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169668-B1 | HERBICIDAL PYRIDAZINONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-04 | — | — | EP | disclosed |