Phosphoribosyl Pyrophosphate

Phosphoribosyl Pyrophosphate

SCHEMBL21330

O=P(O)(O)OC[C@H]1OC(OP(=O)(O)OP(=O)(O)O)[C@H](O)[C@@H]1O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 1/20 0.64
IGF2R P11717 4/20 0.57
AMDHD2 Q9Y303 1/20 0.47
P2RY14 Q15391 6/20 0.46
B4GALT1 P15291 1/20 0.46
P2RY2 P41231 5/20 0.44
P2RY6 Q15077 5/20 0.44
P2RY4 P51582 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoribosyl Pyrophosphate SCHEMBL187952 1.00 FBP1 (0.64) FBP1IGF2RAMDHD2P2RY14B4GALT1
Phosphoribosyl Pyrophosphate SCHEMBL28174133 1.00 FBP1 (0.64) FBP1IGF2RAMDHD2P2RY14B4GALT1
Phosphoribosyl Pyrophosphate SCHEMBL28209513 1.00 FBP1 (0.64) FBP1IGF2RAMDHD2P2RY14B4GALT1
Phosphoribosyl Pyrophosphate SCHEMBL16018854 1.00 FBP1 (0.64) FBP1IGF2RAMDHD2P2RY14B4GALT1
Phosphoribosyl Pyrophosphate SCHEMBL30360449 0.98 FBP1 (0.62) FBP1IGF2RAMDHD2P2RY14B4GALT1
SCHEMBL1332683 0.87 FBP1 (0.72) FBP1IGF2RAMDHD2P2RY2
SCHEMBL1702604 0.87 FBP1 (0.72) FBP1IGF2RAMDHD2P2RY2
SCHEMBL3504366 0.86 FBP1 (0.66) FBP1IGF2RAMDHD2P2RY14B4GALT1
SCHEMBL18710785 0.85 FBP1 (0.70) FBP1IGF2RAMDHD2P2RY14B4GALT1
SCHEMBL8847405 0.85 FBP1 (0.70) FBP1IGF2RAMDHD2P2RY14B4GALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111184133-A Pet health product and preparation method thereof 张琦 2020-05-22 CN claimed
US-9644226-B2 Method for producing vectors containing a gene coding for an enzyme having reduced or deactivated feedback inhibition and the use thereof for producing amino acids and nucleotides FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2017-05-09 US claimed
US-20150284760-A1 METHOD FOR PRODUCING VECTORS CONTAINING A GENE CODING FOR AN ENZYME HAVING REDUCED OR DEACTIVATED FEEDBACK INHIBITION AND THE USE THEREOF FOR PRODUCING AMINO ACIDS AND NUCLEOTIDES FORSCHUNGSZENTRUM JUELICH GMBH (DE) 2015-10-08 US claimed
WO-2015069860-A1 BIOLOGICAL PRODUCTION OF NAD PRECURSORS AND ANALOGS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2015-05-14 WO claimed
EP-2192905-A2 METHOD FOR THE SELECTIVE THERAPY OF DISEASE Lubin, Adam (US) 2010-06-09 EP claimed
WO-2009032057-A2 METHOD FOR THE SELECTIVE THERAPY OF DISEASE LUBIN ADAM (US) 2009-03-12 WO claimed
EP-0205586-B1 COMPOSITION COMPRISING UDPG AND OTHER ANTI-TUMOR DRUGS FOR TREATMENT OF TUMORS MEMORIAL HOSPITAL CANCER (US) 1994-06-22 EP claimed
EP-0406436-A1 PROCESS FOR PREPARING 5'-INOSINIC ACID KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-01-09 EP claimed
WO-1986003678-A1 COMPOSITION AND METHOD FOR TREATMENT OF TUMORS WITH UDPG MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES (US) 1986-07-03 WO claimed
CN-122075713-A Deaminase and use of transaminase in the treatment of polyglutamine diseases 2026-05-26 CN disclosed
EP-4720100-A1 MODIFIED VECTORS CSL Behring LLC (US) 2026-04-08 EP disclosed
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF OSPEDALE SAN RAFFAELE S.R.L. (IT) 2026-01-22 US disclosed
CN-120137864-A Recombinant microorganism for producing L-histidine and application thereof 北京绿色康成生物技术有限公司 2025-06-13 CN disclosed
CN-120137863-A Recombinant microorganism and application thereof in fermentation production of L-histidine 北京绿色康成生物技术有限公司 2025-06-13 CN disclosed
EP-0458070-A1 Cytidine analogue resistance gene DNA and its use Takeda Chemical Industries, Ltd. (JP) 1991-11-27 EP disclosed
EP-0406436-A1 PROCESS FOR PREPARING 5'-INOSINIC ACID KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-01-09 EP disclosed
WO-1990014009-A1 THERAPEUTIC APPLICATION OF AN ANTI-INVASION COMPOUND THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1990-11-29 WO disclosed
US-4885245-A CONTACTING GENETICALLY ENGINEERED CORYNEFORM BACTERIUM WITH APPROPRIATE RAW MATERIALS AJINOMOTO CO., INC. (JP) 1989-12-05 US disclosed
WO-1986003678-A1 COMPOSITION AND METHOD FOR TREATMENT OF TUMORS WITH UDPG MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES (US) 1986-07-03 WO disclosed
EP-0170257-A2 Process for producing l-tryptophan AJINOMOTO CO., INC. (JP) 1986-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022384-A1 ASPARAGINE SYNTHETASE INHIBITORS AND USES THEREOF ASNS, AARS1, NARS1 FBP1 693/4885IGF2R 3320/4885AMDHD2 3361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.