Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.46 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.46 |
| ▸ | IGF2R | P11717 | 1/20 | 0.45 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.45 |
| ▸ | AMY2A | P04746 | 3/20 | 0.44 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.43 |
| ▸ | SELE | P16581 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 3/20 | 0.42 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032277 | 0.92 | AMY1A (0.54) | AMY1ALGALS8LGALS3LGALS4IGF2R | |
| SCHEMBL27279098 | 0.86 | AMY1A (0.51) | AMY1ALGALS8LGALS3LGALS4IGF2R | |
| SCHEMBL16506646 | 0.84 | LGALS8 (0.56) | AMY1ALGALS8LGALS3LGALS4ENGASE | |
| SCHEMBL12595429 | 0.84 | LGALS8 (0.56) | AMY1ALGALS8LGALS3LGALS4ENGASE | |
| SCHEMBL12648833 | 0.84 | LGALS8 (0.56) | AMY1ALGALS8LGALS3LGALS4ENGASE | |
| SCHEMBL24495313 | 0.84 | LGALS8 (0.56) | AMY1ALGALS8LGALS3LGALS4ENGASE | |
| SCHEMBL16510207 | 0.84 | LGALS8 (0.56) | AMY1ALGALS8LGALS3LGALS4ENGASE | |
| SCHEMBL12595483 | 0.84 | LGALS8 (0.56) | AMY1ALGALS8LGALS3LGALS4ENGASE | |
| SCHEMBL16869952 | 0.83 | AMY1A (0.47) | AMY1AIGF2RCD209SELESTAT3 | |
| SCHEMBL16587627 | 0.83 | AMY1A (0.47) | AMY1AIGF2RCD209SELESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10408783-B2 | Electrochemical methods and compounds for the detection of enzymes | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2019-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10408783-B2 | Electrochemical methods and compounds for the detection of enzymes | EPX, DNASE1, DERA | AMY1A 578/4885LGALS8 1316/4885LGALS3 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.