Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335342 | 0.91 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1FOLH1F10POLB | |
| SCHEMBL22693640 | 0.86 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1F10POLBALDH1A1 | |
| SCHEMBL16657546 | 0.86 | TRPA1 (0.44) | HSP90AA1HSP90AB1FOLH1F10POLB | |
| SCHEMBL22693634 | 0.85 | HTT (0.41) | HSP90AA1HSP90AB1FOLH1F10POLB | |
| SCHEMBL23425468 | 0.84 | POLB (0.42) | FOLH1POLBBACE1TRPA1HIF1A | |
| SCHEMBL25741233 | 0.82 | FOLH1 (0.52) | FOLH1POLBBACE1TRPA1HIF1A | |
| SCHEMBL2523725 | 0.81 | AKR1C3 (0.40) | FOLH1AKR1C3AKR1C2POLBLMNA | |
| SCHEMBL29308145 | 0.81 | FOLH1 (0.46) | FOLH1POLBBACE1TRPA1HIF1A | |
| SCHEMBL2793289 | 0.79 | ALOX5 (0.48) | FOLH1POLBBACE1HIF1ATSHR | |
| SCHEMBL26723929 | 0.78 | POLB (0.37) | FOLH1POLBBACE1TRPA1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10406246-B2 | Double-labeled probe for molecular imaging and use thereof | Deutsches Kresbsforschungszentrum (DE) | 2019-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10406246-B2 | Double-labeled probe for molecular imaging and use thereof | CD47, ANXA5, CD44 | HSP90AA1 2389/4885HSP90AB1 1660/4885FOLH1 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.