Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16657546 | 0.95 | TRPA1 (0.44) | HSP90AA1HSP90AB1RNASEH1ALDH1A1LMNA | |
| SCHEMBL22693634 | 0.93 | HTT (0.41) | HSP90AA1HSP90AB1RNASEH1ALDH1A1LMNA | |
| SCHEMBL22693640 | 0.92 | ALDH1A1 (0.43) | HSP90AA1HSP90AB1RNASEH1ALDH1A1LMNA | |
| SCHEMBL21335348 | 0.91 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1RNASEH1ALDH1A1LMNA | |
| SCHEMBL2523725 | 0.89 | AKR1C3 (0.40) | LMNATSHRPOLBFOLH1PTGS1 | |
| SCHEMBL545256 | 0.80 | HTT (0.48) | ALDH1A1LMNATSHRGAAHTT | |
| SCHEMBL13074723 | 0.80 | EGFR (0.46) | ALDH1A1LMNATSHRALOX12HIF1A | |
| SCHEMBL23629772 | 0.79 | HTT (0.47) | ALDH1A1LMNATSHRGAAHTT | |
| SCHEMBL935095 | 0.79 | HTT (0.47) | ALDH1A1LMNATSHRGAAHTT | |
| SCHEMBL935126 | 0.79 | HTT (0.47) | ALDH1A1LMNATSHRGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11020493-B2 | Double-labeled probe for molecular imaging and use thereof | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2021-06-01 | — | — | US | disclosed |
| US-20200368374-A1 | A DOUBLE-LABELED PROBE FOR MOLECULAR IMAGING AND USE THEREOF | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2020-11-26 | — | — | US | disclosed |
| US-10406246-B2 | Double-labeled probe for molecular imaging and use thereof | Deutsches Kresbsforschungszentrum (DE) | 2019-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11020493-B2 | Double-labeled probe for molecular imaging and use thereof | CD47, ANXA5, CD44 | HSP90AA1 2389/4885HSP90AB1 1660/4885RNASEH1 3213/4885 |
| US-10406246-B2 | Double-labeled probe for molecular imaging and use thereof | CD47, ANXA5, CD44 | HSP90AA1 2389/4885HSP90AB1 1660/4885RNASEH1 3213/4885 |
| US-20200368374-A1 | A DOUBLE-LABELED PROBE FOR MOLECULAR IMAGING AND USE THEREOF | ANXA4, ANXA5, ANXA1 | HSP90AA1 4117/4885HSP90AB1 3046/4885RNASEH1 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.