Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21335565 | 0.86 | NPSR1 (0.59) | ALDH1A1MAPTSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL21335672 | 0.80 | MAPT (0.46) | ALDH1A1MAPTSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL18247728 | 0.80 | CYP2A6 (0.40) | ALDH1A1MAPTSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL18247574 | 0.78 | CCR9 (0.39) | ALDH1A1MAPTSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL18258135 | 0.78 | MAPT (0.45) | ALDH1A1MAPTSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL18247762 | 0.77 | GPR35 (0.56) | ALDH1A1MAPTSMN1; SMN2HPGDACSS2 | |
| SCHEMBL4784169 | 0.76 | PTGER4 (0.43) | ALDH1A1SMN1; SMN2HPGDCA12CYP1A2 | |
| SCHEMBL18247416 | 0.74 | NOD2 (0.49) | ALDH1A1MAPTSMN1; SMN2NPSR1HPGD | |
| SCHEMBL20853273 | 0.72 | PTGER4 (0.44) | ALDH1A1MAPTSMN1; SMN2NPSR1RXFP1 | |
| SCHEMBL15553394 | 0.71 | CYP2A6 (0.41) | MAPTPTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407407-B2 | Benzoimidazole derivatives as PAD4 inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10407407-B2 | Benzoimidazole derivatives as PAD4 inhibitors | PADI4, PADI1, PADI2 | ALDH1A1 209/4885MAPT 4738/4885SMN1; SMN2 4198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.