Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18458644 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2AKDM4EGRM2ALDH1A1 | |
| SCHEMBL19631841 | 0.73 | MEN1 (0.34) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL104455 | 0.71 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8648555 | 0.71 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24034121 | 0.70 | — | — | |
| SCHEMBL25823328 | 0.70 | OPRM1 (0.36) | ALDH1A1 | |
| SCHEMBL19631843 | 0.70 | OPRM1 (0.34) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18458361 | 0.69 | KMT2A (0.38) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL20438382 | 0.69 | ALOX15 (0.38) | — | |
| SCHEMBL12000726 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328853-B1 | SUBSTITUTED AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS SA (ES) | 2019-09-11 | — | — | EP | disclosed |