SCHEMBL104455

SCHEMBL104455

CC(C)CCN1CCOCC1

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
ALDH1A1 P00352 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KEAP1 Q14145 1/20 0.46
USP2 O75604 1/20 0.43
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8648555 1.00 KDM4E (0.47) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL14406177 0.92 KDM4E (0.43) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL438497 0.86 MEN1 (0.38) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL105227 0.86 KEAP1 (0.54) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL441441 0.85 KEAP1 (0.52) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL28575023 0.84 LMNA (0.46) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL25299334 0.84 USP2 (0.52) KDM4EALDH1A1SMN1; SMN2KEAP1USP2
SCHEMBL1453895 0.84 USP2 (0.52) KDM4EALDH1A1SMN1; SMN2KEAP1USP2
SCHEMBL8428226 0.84 MEN1 (0.39) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2
SCHEMBL8106724 0.83 SMN1; SMN2 (0.50) KDM4EMEN1KMT2AALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1024 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1073553-C Process for producing N-arylhydroxylamines and N-hetarylhydroxylamines BASF AG (DE) 2001-10-24 CN claimed
US-6031106-A Process and intermediate products for preparing pyridyl-4-fluoroanilines BASF AKTIENGESELLSCHAFT (DE) 2000-02-29 US claimed
EP-0805797-B1 PROCESS FOR PRODUCING N-ARYLHYDROXYLAMINES AND N-HETARYLHYDROXYLAMINES BASF AG (DE) 1999-04-07 EP claimed
US-5831093-A CATALYTIC HYDROGENATION OF NITRO COMPOUNDS BASF AKTIENGESESCHAFT (DE) 1998-11-03 US claimed
CN-1169715-A Process for producing N-arylhydroxylamines and N-hetarylhydroxylamines BASF AG (DE) 1998-01-07 CN claimed
EP-0805797-A1 PROCESS FOR PRODUCING N-ARYLHYDROXYLAMINES AND N-HETARYLHYDROXYLAMINES BASF AKTIENGESELLSCHAFT (DE) 1997-11-12 EP claimed
WO-1996022967-A1 PROCESS FOR PRODUCING N-ARYLHYDROXYLAMINES AND N-HETARYLHYDROXYLAMINES BASF AKTIENGESELLSCHAFT (DE) 1996-08-01 WO claimed
US-20240239792-A1 MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF ASIA VISION LIMITED (CN) 2024-07-18 US disclosed
US-12037323-B2 Uracil derivatives as Mer-AXL inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2024-07-16 US disclosed
US-12037344-B2 NLRP3 modulators INNATE TUMOR IMMUNITY, INC (US) 2024-07-16 US disclosed
US-12037344-B2 NLRP3 modulators INNATE TUMOR IMMUNITY, INC (US) 2024-07-16 US disclosed
WO-2024147972-A2 DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF THOMAS JEFFERSON UNIVERSITY (US) 2024-07-11 WO disclosed
US-12024519-B2 Fused ring derivative having MGAT-2 inhibitory activity SHIONOGI & CO., LTD. (JP) 2024-07-02 US disclosed
US-20070010540-A1 Crystal structure of liganded cFMS kinase domain SHEWCHUK LISA M 2007-01-11 US disclosed
US-7160907-B2 Pleuromutilin derivatives SMITHKLINE BEECHAM P.L.C. (GB) 2007-01-09 US disclosed
CN-1073553-C Process for producing N-arylhydroxylamines and N-hetarylhydroxylamines BASF AG (DE) 2001-10-24 CN disclosed
EP-0805797-B1 PROCESS FOR PRODUCING N-ARYLHYDROXYLAMINES AND N-HETARYLHYDROXYLAMINES BASF AG (DE) 1999-04-07 EP disclosed
US-5831093-A CATALYTIC HYDROGENATION OF NITRO COMPOUNDS BASF AKTIENGESESCHAFT (DE) 1998-11-03 US disclosed
US-5773437-A UROGENITAL DISORDERS SUCH AS DYSURIA NIPPON CHEMIPHAR CO., LTD. (JP) 1998-06-30 US disclosed
CN-1169715-A Process for producing N-arylhydroxylamines and N-hetarylhydroxylamines BASF AG (DE) 1998-01-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239792-A1 MODULATORS OF BCL-2 OR BCL-2/BCL-XL AND USES THEREOF BCL2, BCL2L2, BCL2L1 KDM4E 3505/4885MEN1 4422/4885KMT2A 3421/4885
US-12037344-B2 NLRP3 modulators NLRP3, NLRP1, PYCARD KDM4E 3888/4885MEN1 3081/4885KMT2A 4247/4885
US-12037323-B2 Uracil derivatives as Mer-AXL inhibitors MERTK, DAPK1, AXL KDM4E 3521/4885MEN1 2456/4885KMT2A 3563/4885
US-20070010540-A1 Crystal structure of liganded cFMS kinase domain FAM20C, FRS2, FRK KDM4E 4461/4885MEN1 1516/4885KMT2A 3069/4885
US-12024519-B2 Fused ring derivative having MGAT-2 inhibitory activity MGAT2, MGAT1, ACAT2 KDM4E 2897/4885MEN1 3340/4885KMT2A 213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.