Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17972739 | 0.93 | LMNA (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL13531477 | 0.88 | SMN1; SMN2 (0.71) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11990340 | 0.86 | SMN1; SMN2 (0.73) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL40348 | 0.86 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL18594580 | 0.81 | SMN1; SMN2 (0.83) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11990353 | 0.81 | LMNA (0.64) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL17972790 | 0.80 | SMN1; SMN2 (0.63) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL14288938 | 0.79 | LMNA (0.69) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL11990357 | 0.78 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2L3MBTL1HTTMAPT | |
| SCHEMBL8389256 | 0.77 | SMN1; SMN2 (0.74) | LMNASMN1; SMN2L3MBTL1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2920157-B1 | DI-MACROCYCLES | LUMIPHORE INC (US) | 2019-09-11 | — | — | EP | disclosed |