Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.66 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.66 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | CDC42 | P60953 | 1/20 | 0.66 |
| ▸ | RAC1 | P63000 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090654 | 0.89 | TDP1 (0.63) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL13063821 | 0.87 | TDP1 (0.71) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL31619540 | 0.87 | TDP1 (0.71) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL506523 | 0.87 | TDP1 (0.71) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL3280876 | 0.87 | TDP1 (0.71) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL11725043 | 0.86 | PTGS2 (0.66) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL14036827 | 0.85 | TDP1 (0.69) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL29156025 | 0.85 | TDP1 (0.69) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL13592731 | 0.85 | TDP1 (0.69) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL505811 | 0.84 | TDP1 (0.77) | TDP1L3MBTL1PTGS2AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10640484-B2 | Method for producing (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imidazolidine-2,4-dione and intermediate for producing same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2020-05-05 | — | — | US | disclosed |
| US-20190276428-A1 | METHOD FOR PRODUCING (R)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND INTERMEDIATE FOR PRODUCING SAME | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276428-A1 | METHOD FOR PRODUCING (R)-5-(3,4-DIFLUOROPHENYL)-5-[(3-METHYL-2-OXOPYRIDIN-1(2H)-YL)METHYL]IMIDAZOLIDINE-2,4-DIONE AND INTERMEDIATE FOR PRODUCING SAME | DHPS, MRM1, PRMT5 | TDP1 2242/4885L3MBTL1 4636/4885PTGS2 641/4885 |
| US-10640484-B2 | Method for producing (R)-5-(3,4-difluorophenyl)-5-[(3-methyl-2-oxopyridin-1(2H)-yl)methyl]imidazolidine-2,4-dione and intermediate for producing same | DHPS, MRM1, PRMT5 | TDP1 2242/4885L3MBTL1 4636/4885PTGS2 641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.