Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 14/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342024 | 0.84 | KDM2B (0.48) | KDM2BDRD2DRD3FPR1 | |
| SCHEMBL21341950 | 0.83 | HTR2A (0.48) | DRD2DRD3FPR1 | |
| SCHEMBL21342317 | 0.83 | DRD2 (0.46) | KDM2BDRD2FPR1 | |
| SCHEMBL21342427 | 0.83 | FPR1 (0.48) | KDM2BDRD2FPR1 | |
| SCHEMBL21342436 | 0.81 | DRD2 (0.44) | KDM2BDRD2DRD3FPR1 | |
| SCHEMBL21341956 | 0.81 | DRD2 (0.39) | KDM2BDRD2FPR1 | |
| SCHEMBL20001273 | 0.75 | FPR1 (0.48) | KDM2BFPR1 | |
| SCHEMBL23654002 | 0.74 | FPR1 (0.53) | KDM2BFPR1 | |
| SCHEMBL21341995 | 0.71 | PDE4B (0.46) | — | |
| SCHEMBL22778127 | 0.69 | KDM2B (0.53) | KDM2BDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |