Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15649592 | 0.84 | PDE4B (0.54) | PDE4BALDH1A1MMP1MMP9MMP13 | |
| SCHEMBL21342033 | 0.80 | PDE4B (0.45) | PDE4BALDH1A1GPR119MEN1KMT2A | |
| SCHEMBL21342468 | 0.80 | PDE4B (0.45) | PDE4BALDH1A1GPR119MEN1KMT2A | |
| SCHEMBL21359263 | 0.78 | BCL9 (0.60) | PDE4BALDH1A1MEN1KMT2AUSP30 | |
| SCHEMBL19405061 | 0.78 | GPR119 (0.52) | PDE4BTRPV3GPR119MAPTUSP30 | |
| SCHEMBL28297784 | 0.78 | KDM4E (0.50) | PDE4BTRPV3GPR119MAPTHPGDS | |
| SCHEMBL28297774 | 0.78 | KDM4E (0.50) | PDE4BTRPV3GPR119MAPTHPGDS | |
| SCHEMBL31383614 | 0.77 | ALDH1A1 (0.47) | PDE4BTRPV3ALDH1A1MMP1MMP9 | |
| SCHEMBL15307876 | 0.77 | KDM2B (0.57) | ALDH1A1MAPTMEN1KMT2ASTS | |
| SCHEMBL28782629 | 0.77 | PDE4B (0.54) | PDE4BSCN9AALDH1A1MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |