Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342499 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1KDM1AKMT2AMAOA | |
| SCHEMBL21342015 | 0.78 | KDM1A (0.44) | SMN1; SMN2ALDH1A1KDM1AKMT2AL3MBTL1 | |
| SCHEMBL15415176 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL21342013 | 0.75 | FPR2 (0.59) | — | |
| Hydrochloric Acid SCHEMBL16333534 | 0.74 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL21342338 | 0.73 | KDM1A (0.51) | SMN1; SMN2ALDH1A1KDM1AMAOAMAOB | |
| SCHEMBL8348748 | 0.71 | GRM2 (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL19972421 | 0.70 | PDE4A (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL19972374 | 0.70 | PDE4A (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL19972419 | 0.70 | PDE4A (0.52) | SMN1; SMN2ALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |