Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | FPR1 | P21462 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342495 | 0.89 | FPR1 (0.50) | KDM1ASMN1; SMN2CYP3A4CYP2C19FPR1 | |
| SCHEMBL21342429 | 0.85 | SMN1; SMN2 (0.51) | KDM1ASMN1; SMN2FPR1KMT2AALDH1A1 | |
| SCHEMBL21342490 | 0.85 | SMN1; SMN2 (0.51) | KDM1ASMN1; SMN2FPR1KMT2AALDH1A1 | |
| SCHEMBL21342018 | 0.83 | KDM1A (0.47) | KDM1ACYP3A4CYP2C19FPR1FPR2 | |
| SCHEMBL21342410 | 0.83 | KDM1A (0.47) | KDM1ACYP3A4CYP2C19FPR1FPR2 | |
| SCHEMBL21342013 | 0.81 | FPR2 (0.59) | FPR1FPR2 | |
| SCHEMBL21342456 | 0.80 | FPR1 (0.53) | KDM1AFPR1ALDH1A1L3MBTL1FPR2 | |
| SCHEMBL21342340 | 0.78 | LMNA (0.51) | KDM1ASMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL21342016 | 0.78 | SMN1; SMN2 (0.43) | KDM1ASMN1; SMN2CYP3A4CYP2C19KMT2A | |
| SCHEMBL19988732 | 0.75 | FPR1 (0.55) | SMN1; SMN2CYP3A4CYP2C19FPR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |