Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 12/20 | 0.59 |
| ▸ | FPR1 | P21462 | 15/20 | 0.57 |
| ▸ | CCR3 | P51677 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342492 | 0.90 | FPR1 (0.71) | FPR2FPR1CCR3 | |
| SCHEMBL21342569 | 0.86 | FPR1 (0.71) | FPR2FPR1CCR3 | |
| SCHEMBL21342493 | 0.86 | FPR1 (0.71) | FPR2FPR1CCR3 | |
| SCHEMBL21342015 | 0.81 | KDM1A (0.44) | FPR2FPR1 | |
| SCHEMBL21333912 | 0.79 | FPR2 (0.60) | FPR2FPR1CCR3 | |
| SCHEMBL21331928 | 0.79 | FPR2 (0.60) | FPR2FPR1CCR3 | |
| SCHEMBL21341999 | 0.78 | FPR1 (0.64) | FPR2FPR1 | |
| SCHEMBL21332006 | 0.78 | FPR1 (0.64) | FPR2FPR1 | |
| SCHEMBL21331992 | 0.77 | FPR1 (0.73) | FPR2FPR1 | |
| SCHEMBL21342328 | 0.77 | FPR1 (0.73) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |