Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 14/20 | 0.71 |
| ▸ | FPR2 | P25090 | 11/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342493 | 1.00 | FPR1 (0.71) | FPR1FPR2SMN1; SMN2CCR3 | |
| SCHEMBL21342013 | 0.86 | FPR2 (0.59) | FPR1FPR2CCR3 | |
| SCHEMBL21342492 | 0.85 | FPR1 (0.71) | FPR1FPR2CCR3 | |
| SCHEMBL21342429 | 0.82 | SMN1; SMN2 (0.51) | FPR1FPR2SMN1; SMN2 | |
| SCHEMBL21342490 | 0.82 | SMN1; SMN2 (0.51) | FPR1FPR2SMN1; SMN2 | |
| SCHEMBL21342499 | 0.76 | SMN1; SMN2 (0.52) | FPR1FPR2SMN1; SMN2 | |
| SCHEMBL21332006 | 0.75 | FPR1 (0.64) | FPR1FPR2 | |
| SCHEMBL21341999 | 0.75 | FPR1 (0.64) | FPR1FPR2 | |
| SCHEMBL21342327 | 0.74 | FPR1 (0.73) | FPR1FPR2 | |
| SCHEMBL21342017 | 0.74 | FPR1 (0.60) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |