Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21344672 | 0.84 | VNN1 (0.36) | CYP3A4 | |
| SCHEMBL21344270 | 0.83 | KMT2A (0.40) | CYP2C9CYP2C19CYP3A4CYP11B2CYP1A2 | |
| SCHEMBL22992155 | 0.83 | CYP3A4 (0.44) | CYP2C9CYP2C19CYP3A4CYP1A2SMN1; SMN2 | |
| SCHEMBL22992040 | 0.81 | CYP3A4 (0.47) | CYP2C9CYP3A4CYP1A2CYP2D6USP2 | |
| SCHEMBL22992059 | 0.81 | ACACA (0.33) | — | |
| SCHEMBL21344257 | 0.81 | PSEN1 (0.36) | CYP2C9CYP2C19CYP3A4SLC9A1CYP11B1 | |
| SCHEMBL22992061 | 0.81 | NAMPT (0.37) | CYP2C9CYP2C19CYP1A2SMN1; SMN2CYP2D6 | |
| SCHEMBL21343899 | 0.81 | USP2 (0.31) | CYP3A4USP2 | |
| SCHEMBL21344679 | 0.81 | NAMPT (0.42) | CYP2C9CYP11B1CYP11B2CYP2D6USP2 | |
| SCHEMBL22992203 | 0.81 | NAMPT (0.36) | CYP3A4RBP4PARP1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| US-12043599-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2024-07-23 | — | — | US | disclosed |
| EP-3762378-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-02-18 | — | — | US | disclosed |
| WO-2019170745-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210047274-A1 | HERBICIDAL COMPOUNDS | DDT, CBR3, GLRX3 | CYP2C9 73/4885CYP2C19 286/4885CYP3A4 245/4885 |
| US-12043599-B2 | Herbicidal compounds | DDT, CBR3, GLRX3 | CYP2C9 73/4885CYP2C19 286/4885CYP3A4 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.