Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28322849 | 0.78 | CSNK2A1 (0.38) | ROCK2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL26556079 | 0.76 | ROCK2 (0.37) | ROCK2PSMB5NPC1RAB9A | |
| SCHEMBL2274451 | 0.76 | ROCK2 (0.46) | ROCK2ALDH1A1 | |
| SCHEMBL30733666 | 0.76 | ROCK2 (0.46) | ROCK2ALDH1A1 | |
| SCHEMBL30670217 | 0.74 | HPGD (0.41) | ROCK2NPY5RALDH1A1MEN1KMT2A | |
| SCHEMBL1790973 | 0.74 | ALDH1A1 (0.37) | ROCK2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28540908 | 0.73 | S1PR1 (0.36) | ROCK2NPC1RAB9A | |
| SCHEMBL301559 | 0.73 | TAS1R3 (0.40) | ROCK2PSMB5ALDH1A1MEN1KMT2A | |
| SCHEMBL381945 | 0.73 | CD274 (0.40) | ROCK2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29778140 | 0.73 | CYP2A6 (0.48) | ROCK2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787827-B2 | Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions | DONGGUAN STEPHEN CATALYST CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
| WO-2019170163-A1 | TRIARYL PHOSPHINE LIGANDS, PREPARATION METHOD THEREFOR, AND USE IN CATALYSING COUPLING REACTIONS | 东莞市均成高新材料有限公司 | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787827-B2 | Triaryl phosphine ligands, preparation method therefor, and use in catalyzing coupling reactions | WEE1, WEE2, NOTUM | ROCK2 3615/4885PSMB5 3356/4885METAP2 1797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.