SCHEMBL21349166

SCHEMBL21349166

CC(C)C(=O)CC(N)C=O

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 3/20 0.31
GRIA2 P42262 2/20 0.31
GRIA4 P48058 2/20 0.31
GRIK3 Q13003 2/20 0.31
GRIK5 Q16478 2/20 0.31
GRIK2 Q13002 2/20 0.31
GRIA1 P42261 1/20 0.31
PAX8 Q06710 1/20 0.31
ENPEP Q07075 2/20 0.30
CPT2 P23786 1/20 0.30
CPT1A P50416 1/20 0.30
GABRP O00591 4/20 0.30
GABRD O14764 4/20 0.30
GABRA1 P14867 4/20 0.30
GABRB1 P18505 4/20 0.30
GABRG2 P18507 4/20 0.30
GABRB3 P28472 4/20 0.30
GABRA5 P31644 4/20 0.30
GABRA3 P34903 4/20 0.30
GABRA2 P47869 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12809879 0.75
SCHEMBL26632580 0.75
SCHEMBL3973664 0.75 ALDH1A1 (0.32)
SCHEMBL24040207 0.74
SCHEMBL25083763 0.74 ENPEP (0.39) ENPEPCPT2CPT1AGABRPGABRD
SCHEMBL23464806 0.74
SCHEMBL10519890 0.72
SCHEMBL5686558 0.72
SCHEMBL7397717 0.72
SCHEMBL469068 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11173109-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid ADOCIA (FR) 2021-11-16 US disclosed
US-20190274954-A1 Copositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid ADOCIA (FR) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190274954-A1 Copositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid IAPP, GLP1R, INSR GRIK1 2672/4885GRIA2 1273/4885GRIA4 789/4885
US-11173109-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid IAPP, INSR, GLP1R GRIK1 2464/4885GRIA2 1548/4885GRIA4 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.