Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.55 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21352382 | 0.92 | GPR119 (0.50) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL21352395 | 0.88 | GPR119 (0.47) | GPR119NAMPTKDM4EPKMHPGDS | |
| SCHEMBL3436365 | 0.86 | GPR119 (0.58) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL21352380 | 0.86 | HPGDS (0.50) | GPR119MAPTHPGDSMEN1KMT2A | |
| SCHEMBL1613087 | 0.85 | GPR119 (0.56) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL21953943 | 0.85 | GPR119 (0.56) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL30749320 | 0.84 | GPR119 (0.53) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL2102993 | 0.84 | GPR119 (0.53) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL21885666 | 0.84 | GPR119 (0.55) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL73493 | 0.84 | GPR119 (0.55) | GPR119NAMPTKDM4ETHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |