Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2102993 | 1.00 | GPR119 (0.53) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL27223620 | 0.86 | HPGDS (0.48) | GPR119MAPTHPGDSMEN1KMT2A | |
| SCHEMBL12712644 | 0.86 | NAMPT (0.47) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL21352374 | 0.84 | GPR119 (0.55) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL3436365 | 0.84 | GPR119 (0.58) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL21953943 | 0.83 | GPR119 (0.56) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL1613087 | 0.83 | GPR119 (0.56) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL15156769 | 0.82 | ALDH1A1 (0.54) | GPR119KDM4ETHRBMAPTSTS | |
| SCHEMBL2099835 | 0.82 | GPR119 (0.48) | GPR119NAMPTKDM4ETHRBMAPT | |
| SCHEMBL2099834 | 0.82 | GPR119 (0.48) | GPR119NAMPTKDM4ETHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |