SCHEMBL2135458

SCHEMBL2135458

[Li]C(C)(CC(C)CC)c1cccc(C([Li])(C)CC(C)CC)c1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
GRIN1 Q05586 4/20 0.32
GRIN2A Q12879 4/20 0.32
GRIN2D O15399 3/20 0.32
GRIN2C Q14957 3/20 0.32
GRIN2B Q13224 2/20 0.32
HTR2A P28223 2/20 0.32
HTR2B P41595 2/20 0.32
RORC P51449 1/20 0.32
HTR2C P28335 1/20 0.32
LMNA P02545 2/20 0.31
SIGMAR1 Q99720 1/20 0.31
MAPT P10636 1/20 0.31
ADRA2C P18825 1/20 0.31
SLC6A4 P31645 1/20 0.31
ADRA1A P35348 1/20 0.31
DRD3 P35462 1/20 0.31
OPRK1 P41145 1/20 0.31
HDAC4 P56524 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7751692 0.87 GRIN1 (0.39) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL1901712 0.84 RORC (0.35) ESR1ESR2RORCLMNANPC1
SCHEMBL11704776 0.83 L3MBTL1 (0.39) LMNAMAPTSMN1; SMN2
SCHEMBL4015805 0.79 GRIN1 (0.40) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL9308983 0.78 GRIA4 (0.35) ESR1ESR2GRIN1GRIN2AGRIN2D
SCHEMBL20286451 0.78 ESR1 (0.32) ESR1ESR2GRIN1GRIN2AGRIN2D
SCHEMBL3809392 0.78 GRIN1 (0.35) ESR1ESR2GRIN1GRIN2AGRIN2D
SCHEMBL13808929 0.78 LMNA (0.34) ESR1ESR2GRIN1GRIN2AGRIN2D
SCHEMBL1554734 0.77 TSHR (0.31) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B
SCHEMBL4459760 0.75 GRIN1 (0.31) GRIN1GRIN2AGRIN2DGRIN2CGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5693718-A ADDING A RANDOMIZING AGENT TO THE COMPLETED POLYMERIZATION OF 1,3-BUTADIENE IN A HYDROCARBON SOLVENT USING A LITHIUM INITIATOR; ADDING AND POLYMERIZING A VINYLAROMATIC MONOMER TO FORM A TRIBLOCK POLYMER SHELL OIL COMPANY (US) 1997-12-02 US claimed
US-5464914-A Preparation of a low polydisperse polymer THE DOW CHEMICAL COMPANY (US) 1995-11-07 US claimed
US-4039593-A CAPPING ORGANO-DILITHIUM POLYMERS, N,N,N*,N*-TETRAMETHYLENEDIAMINE ON LITHIUM CORPORATION OF AMERICA (US) 1977-08-02 US claimed
US-3954894-A Organotrilithium polymerization initiators LITHIUM CORPORATION OF AMERICA (US) 1976-05-04 US claimed
EP-4056613-B1 BLOCK POLYMER, POLYMER COMPOSITION, AND ADHESIVE ENEOS MAT CORPORATION (JP) 2026-04-22 EP disclosed
EP-4056612-B1 BLOCK COPOLYMER AND ADHESIVE ENEOS MAT CORPORATION (JP) 2026-02-18 EP disclosed
EP-4692203-A1 POLYMER COMPOSITION AND RUBBER PRODUCT ENEOS Materials Corporation (JP) 2026-02-11 EP disclosed
EP-4692202-A1 POLYMER COMPOSITION AND RUBBER PRODUCT ENEOS Materials Corporation (JP) 2026-02-11 EP disclosed
EP-4692201-A1 POLYMER COMPOSITION AND RUBBER PRODUCT ENEOS Materials Corporation (JP) 2026-02-11 EP disclosed
EP-3988610-B1 POLYMER COMPOSITION, CROSSLINKED POLYMER, AND TIRE ENEOS MAT CORPORATION (JP) 2026-01-28 EP disclosed
US-20260015448-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED PRODUCT, AND TIRE ENEOS MATERIALS CORPORATION (JP) 2026-01-15 US disclosed
US-12497499-B2 Polymer composition production method ENEOS MATERIALS CORPORATION (JP) 2025-12-16 US disclosed
EP-0234512-A2 Crystaline block copolymer and process for producing the same Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-09-02 EP disclosed
US-4634786-A INTERMEDIATES FOR ZIEGLER CATALYSTS LITHIUM CORPORATION OF AMERICA (US) 1987-01-06 US disclosed
US-4501857-A CONJUGATED DIENE POLYMERS USING AN ORGANIC TITANIUM COMPOUND AND LITHIUM HYDROCARBON; CATALYST SELECTIVITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-02-26 US disclosed
US-4367325-A Styrene-butadiene random copolymer and process for the production thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1983-01-04 US disclosed
US-4254238-A Hydrocarbon/ethylene oxide random graft copolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-03 US disclosed
US-4039593-A CAPPING ORGANO-DILITHIUM POLYMERS, N,N,N*,N*-TETRAMETHYLENEDIAMINE ON LITHIUM CORPORATION OF AMERICA (US) 1977-08-02 US disclosed
US-4034021-A Copolymers of pivalolactone and isoprene or butadiene E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-07-05 US disclosed
US-3954894-A Organotrilithium polymerization initiators LITHIUM CORPORATION OF AMERICA (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015448-A1 MODIFIED CONJUGATED DIENE POLYMER AND METHOD FOR PRODUCING SAME, POLYMER COMPOSITION, CROSSLINKED PRODUCT, AND TIRE TRRAP, MALT1, CCT4 ESR1 1764/4885ESR2 1348/4885GRIN1 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.