Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.47 |
| ▸ | NPY4R | P50391 | 6/20 | 0.45 |
| ▸ | NPY1R | P25929 | 4/20 | 0.45 |
| ▸ | NPY2R | P49146 | 3/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSH | P09668 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24178268 | 0.92 | FNTA (0.47) | GNPATSMN1; SMN2KISS1RNPY4RNPY1R | |
| SCHEMBL21167756 | 0.91 | F2 (0.50) | SMN1; SMN2CTSKNPY4RNPY1RNPY2R | |
| SCHEMBL7368582 | 0.90 | GNPAT (0.48) | GNPATSMN1; SMN2KISS1RNPY4RNPY1R | |
| SCHEMBL24736900 | 0.87 | CTSC (0.45) | SMN1; SMN2CTSKNPY4RNPY1RNPY2R | |
| SCHEMBL3134717 | 0.87 | CTSC (0.45) | SMN1; SMN2CTSKNPY4RNPY1RNPY2R | |
| SCHEMBL30533200 | 0.86 | GNPAT (0.70) | GNPATCTSKCTSSKISS1RNPY4R | |
| SCHEMBL11569736 | 0.86 | GNPAT (0.70) | GNPATCTSKCTSSKISS1RNPY4R | |
| SCHEMBL11294449 | 0.86 | GNPAT (0.70) | GNPATCTSKCTSSKISS1RNPY4R | |
| SCHEMBL7373235 | 0.86 | CTSS (0.53) | CTSKCTSSPTPN1CTSLCTSB | |
| SCHEMBL12792618 | 0.85 | KISS1R (0.62) | GNPATKISS1RNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10414796-B2 | Genetic system for producing a proteases inhibitor of a small peptide aldehyde type | CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITÉCNICO NACIONAL (MX) | 2019-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10414796-B2 | Genetic system for producing a proteases inhibitor of a small peptide aldehyde type | SPPL2A, SPPL2B, HM13 | GNPAT 78/4885SMN1; SMN2 4293/4885CTSK 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.