Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 5/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | GRB2 | P62993 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371728 | 0.92 | OPRD1 (0.47) | SMN1; SMN2HRH4GRB2MMP9MMP8 | |
| SCHEMBL7370024 | 0.90 | PSMB5 (0.46) | SMN1; SMN2HRH4MMP9MMP8MMP14 | |
| SCHEMBL21360283 | 0.90 | GNPAT (0.52) | GNPATSMN1; SMN2KISS1RNPY4RNPY1R | |
| SCHEMBL7374882 | 0.89 | CTSS (0.56) | — | |
| SCHEMBL8373858 | 0.86 | HDAC3 (0.42) | SMN1; SMN2HRH4MC4RKISS1RMMP9 | |
| SCHEMBL30028835 | 0.86 | GNPAT (0.53) | GNPATHRH4MC4RKISS1RTACR1 | |
| SCHEMBL24178268 | 0.84 | FNTA (0.47) | GNPATSMN1; SMN2KISS1RNPY4RNPY1R | |
| SCHEMBL6552717 | 0.84 | NPY4R (0.49) | MC4RKISS1RTACR1NPY4RNPY1R | |
| SCHEMBL21167756 | 0.82 | F2 (0.50) | SMN1; SMN2NPY4RCASP1NPY1R | |
| SCHEMBL11294449 | 0.81 | GNPAT (0.70) | GNPATKISS1RNPY4RNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675899-B1 | NOVEL INHIBITORS OF FACTOR Xa | CORVAS INT INC (US) | 1999-03-17 | — | — | EP | disclosed |
| US-5883077-A | PEPTIDES ALDEHYDE ANALOGUES | CORVAS INTERNATIONAL, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739112-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1998-04-14 | — | — | US | disclosed |
| WO-1994013693-A1 | NOVEL INHIBITORS OF FACTOR Xa | CORVAS INTERNATIONAL, INC. (US) | 1994-06-23 | — | — | WO | disclosed |