Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | UBE2N | P61088 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6547008 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1L3MBTL1SLC6A4 | |
| SCHEMBL6546874 | 0.78 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1L3MBTL1SLC6A4 | |
| SCHEMBL23714185 | 0.73 | PNMT (0.37) | LMNAOPRK1MAPTSLC6A4TAAR1 | |
| SCHEMBL3014825 | 0.72 | SLC11A2 (0.46) | ALDH1A1KMT2AKDM4EMEN1PSMD14 | |
| SCHEMBL3082123 | 0.69 | SIGMAR1 (0.52) | KMT2AMEN1SLC6A4TAAR1SLC6A2 | |
| SCHEMBL1145610 | 0.69 | TAAR1 (0.56) | ALDH1A1KMT2AKDM4EMEN1PSMD14 | |
| SCHEMBL515186 | 0.68 | MAPT (0.56) | ALDH1A1KMT2AMEN1LMNACYP1A2 | |
| SCHEMBL19221800 | 0.68 | OPRK1 (0.46) | KMT2AKDM4EMEN1LMNACYP1A2 | |
| SCHEMBL18820847 | 0.68 | OPRK1 (0.46) | KMT2AKDM4EMEN1LMNACYP1A2 | |
| Ammonia Solution, Strong SCHEMBL27683289 | 0.67 | TAAR1 (0.55) | ALDH1A1KMT2AKDM4EMEN1PSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |