Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14543377 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL15462283 | 0.79 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL623218 | 0.79 | TDP1 (0.55) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| Ammonia Solution, Strong SCHEMBL16053585 | 0.77 | TDP1 (0.53) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL11922737 | 0.77 | ALDH1A1 (0.65) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| Hydrochloric Acid SCHEMBL7879022 | 0.77 | TDP1 (0.53) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL18408991 | 0.77 | ADRB1 (0.60) | ALDH1A1KMT2AHTTTSHRLMNA | |
| SCHEMBL14600334 | 0.75 | CHRNA7 (0.55) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL336283 | 0.74 | ADRB1 (0.63) | ALDH1A1MAPTKMT2AHTTMEN1 | |
| SCHEMBL4807592 | 0.74 | ALDH1A1 (0.67) | ALDH1A1MAPTKMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019178510-A1 | TRIAZACYCLODODECANSULFONAMIDE (\"TCD\")-BASED PROTEIN SECRETION INHIBITORS | KEZAR LIFE SCIENCES (US) | 2019-09-19 | — | — | WO | disclosed |