SCHEMBL623218

SCHEMBL623218

Cc1cccc(C)c1N1CCN(c2c(C)cccc2C)C1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 10/20 0.52
MAPT P10636 5/20 0.52
KMT2A Q03164 4/20 0.52
HTT P42858 4/20 0.52
MEN1 O00255 3/20 0.52
KDM4E B2RXH2 1/20 0.52
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
POLB P06746 4/20 0.49
GAA P10253 3/20 0.47
TSHR P16473 4/20 0.46
LMNA P02545 2/20 0.46
MAPK1 P28482 1/20 0.46
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ACHE P22303 1/20 0.43
ADRB1 P08588 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL16053585 0.98 TDP1 (0.53) TDP1ALDH1A1MAPTKMT2AHTT
Hydrochloric Acid SCHEMBL7879022 0.98 TDP1 (0.53) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL11169824 0.91 ALDH1A1 (0.49) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL22279347 0.85 ACHE (0.48) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL18966914 0.82 HTR7 (0.51) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL14543377 0.81 ALDH1A1 (0.53) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL15462283 0.80 ALDH1A1 (0.61) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL21361598 0.79 ALDH1A1 (0.51) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL11922737 0.78 ALDH1A1 (0.65) TDP1ALDH1A1MAPTKMT2AHTT
SCHEMBL10118836 0.78 ADRB1 (0.61) ALDH1A1KMT2AHTTTSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731570-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-29 EP claimed
EP-4568924-A2 METHOD OF SYNTHESIZING COVALENTLY BONDED LATTICES CASE WESTERN RESERVE UNIVERSITY (US) 2025-06-18 EP claimed
CN-120129654-A Synthesis method of covalent bonding lattice 卡斯西部储备大学 2025-06-10 CN claimed
WO-2024264047-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2024-12-26 WO claimed
WO-2024035672-A2 METHOD OF SYNTHESIZING COVALENTLY BONDED LATTICES CASE WESTERN RESERVE UNIVERSITY (US) 2024-02-15 WO claimed
US-10081587-B2 Methods for the synthesis of olefins and derivatives GENOMATICA, INC. (US) 2018-09-25 US claimed
US-20170008828-A1 METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES GENOMATICA, INC. 2017-01-12 US claimed
US-20090155866-A1 METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES GENOMATICA, INC. 2009-06-18 US claimed
EP-4731570-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-29 EP disclosed
EP-4568924-A2 METHOD OF SYNTHESIZING COVALENTLY BONDED LATTICES CASE WESTERN RESERVE UNIVERSITY (US) 2025-06-18 EP disclosed
CN-120129654-A Synthesis method of covalent bonding lattice 卡斯西部储备大学 2025-06-10 CN disclosed
WO-2024264047-A2 GAMMA-GRAPHYNE AND METHODS OF FABRICATION CASE WESTERN RESERVE UNIVERSITY (US) 2024-12-26 WO disclosed
WO-2024035672-A2 METHOD OF SYNTHESIZING COVALENTLY BONDED LATTICES CASE WESTERN RESERVE UNIVERSITY (US) 2024-02-15 WO disclosed
WO-2023137771-A1 METHOD FOR SYNTHESIZING α-ALKYL SUBSTITUTED INDOLE-3-CARBOXALDEHYDE COMPOUND 苏州大学 2023-07-27 WO disclosed
US-20110287988-A1 SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME EUAGORE, LLC 2011-11-24 US disclosed
US-20110183068-A1 COMPOSITION FOR PRODUCTION OF METAL FILM, METHOD FOR PRODUCING METAL FILM AND METHOD FOR PRODUCING METAL POWDER TOSOH CORPORATION (JP) 2011-07-28 US disclosed
EP-2339594-A1 COMPOSITION FOR PRODUCING METAL FILM, METHOD FOR PRODUCING METAL FILM, AND METHOD FOR PRODUCING METAL POWDER Tosoh Corporation (JP) 2011-06-29 EP disclosed
US-7964758-B2 Process for production of 2-(substituted phenyl)-3,3,3-trifluoropropene compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-06-21 US disclosed
US-20100160683-A1 Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2010-06-24 US disclosed
US-6403802-B1 MIXING IN LIQUID MEDIUM STRONG BASE, ARYL HALIDE OR ARYL PSEUDOHALIDE, PRIMARY AND/OR SECONDARY AMINE, NICKEL, PALLADIUM OR PLATINUM COMPOUND, N-HETEROCYCLIC CARBENE SUCH AS IMIDAZOLINE-2-YLIDENE, BIS(IMIDAZOLINE-2-YLIDENE) OR SALTS UNIVERSITY OF NEW ORLEANS RESEARCH & TECHNOLOGY FOUNDATION 2002-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008828-A1 METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES COASY, MTHFD2, FAH TDP1 3460/4885ALDH1A1 232/4885MAPT 1999/4885
US-20110287988-A1 SQUALANE AND ISOSQUALANE COMPOSITIONS AND METHODS FOR PREPARING THE SAME SQLE, FDFT1, COASY TDP1 658/4885ALDH1A1 155/4885MAPT 3566/4885
US-20090155866-A1 METHODS FOR THE SYNTHESIS OF OLEFINS AND DERIVATIVES COASY, MTHFD2, FAH TDP1 3460/4885ALDH1A1 232/4885MAPT 1999/4885
US-10081587-B2 Methods for the synthesis of olefins and derivatives COASY, MTHFD2, FAH TDP1 3460/4885ALDH1A1 232/4885MAPT 1999/4885
US-20100160683-A1 Process for Production of 2-(Substituted Phenyl)-3,3,3-Trifluoropropene Compound PEX3, SCO2, LPO TDP1 4467/4885ALDH1A1 3618/4885MAPT 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.